[Campbell Biology P.400] Based on the large sequence logo, which single nucleotide position ... | Practice Question

Based on the large sequence logo, which single nucleotide position in the 5' UTR upstream of the start codon at position 0 shows the highest conservation and predictive power, indicating its likely importance for ribosome binding?

  • A: Position -1
  • B: Position -10
  • C: Position -16
  • D: Position 5

Explanation

The text explains that ribosome binding sites are conserved stretches of bases upstream of the AUG start codon positions 0, 1, 2 . Looking at the large sequence logo, the stack at position -1 is remarkably tall, indicating extremely high conservation and predictive power for the base G at this position. This makes it a prime candidate for a critical nucleotide within the ribosome binding site.