[Campbell Biology P.1004] Which of the following statements about Toll-like receptors TLRs an... | Practice Question

Which of the following statements about Toll-like receptors TLRs and their functions is FALSE?

  • A: TLR4 recognizes lipopolysaccharide (LPS) on bacterial surfaces and is located on the plasma membrane.
  • B: TLR3 is found on the inner surface of vesicles and binds double-stranded RNA (dsRNA) from viruses.
  • C: TLR9 recognizes flagellin, the main protein of bacterial flagella, and is located on the plasma membrane.
  • D: Binding of pathogen molecules to TLRs triggers innate immune responses.

Explanation

TLR9 recognizes CpG DNA and is located on the inner surface of vesicles. Flagellin is recognized by TLR5, which is located on the plasma membrane. Therefore, statement C is false.