[Campbell Biology P.374] Which statement best describes a key difference between DNA synthes... | Practice Question

Which statement best describes a key difference between DNA synthesis on the leading strand and the lagging strand during replication?

• A: Leading strand synthesis requires DNA ligase, while lagging strand synthesis does not.
• B: The leading strand is synthesized discontinuously, whereas the lagging strand is synthesized continuously.
• C: Only the lagging strand requires an RNA primer for its synthesis.
• D: DNA polymerase III adds nucleotides continuously on the leading strand but discontinuously on the lagging strand.
• E: Single-strand binding proteins are only required for lagging strand synthesis.