[Campbell Biology P.1010] Based on Figure 43.14, which sequence accurately describes the proc... | Practice Question

Based on Figure 43.14, which sequence accurately describes the process of immunoglobulin light-chain production from undifferentiated B cell DNA to the final polypeptide?

  • A: DNA recombination (deletion of introns) -> Transcription -> RNA processing (addition of Cap and Poly-A tail) -> Translation
  • B: DNA recombination (deletion of V and J segments) -> Transcription -> RNA processing (removal of intron) -> Translation
  • C: DNA recombination (deletion of DNA between V and J segments) -> Transcription -> RNA processing (removal of intron, addition of Cap and Poly-A tail) -> Translation
  • D: Transcription -> DNA recombination -> RNA processing -> Translation

Explanation

Figure 43.14 clearly shows the sequence: 1 Recombination deletes DNA between V and J segments, forming a functional gene. 2 This functional gene is transcribed into pre-mRNA. 3 The pre-mRNA undergoes RNA processing intron removal, Cap and Poly-A tail addition to become mRNA. 4 Finally, mRNA is translated into the light-chain polypeptide.