[Campbell Biology P.1054] Which statement accurately distinguishes between the feedback mecha... | Practice Question
Which statement accurately distinguishes between the feedback mechanisms illustrated by secretin signaling and oxytocin signaling?
A: Secretin signaling demonstrates positive feedback, where bicarbonate release amplifies low pH, while oxytocin signaling shows negative feedback, where milk release reduces suckling.
B: Both secretin and oxytocin signaling pathways exhibit negative feedback, aiming to maintain homeostasis by reducing the initial stimulus.
C: Secretin signaling involves negative feedback, as the bicarbonate response reduces the initial low pH stimulus, whereas oxytocin signaling involves positive feedback, as milk release amplifies the suckling stimulus.
D: Secretin signaling and oxytocin signaling are fundamentally different because one is an endocrine pathway and the other is neuroendocrine, making their feedback mechanisms incomparable.
Explanation
The text explicitly states that 'In the case of secretin signaling, the simple endocrine pathway is self-limiting because the response bicarbonate release reduces the stimulus low pH through negative feedback.' For oxytocin, it states 'In oxytocin signaling, the response increases the stimulus, forming a positive-feedback loop that amplifies signaling.' Option C correctly reflects these definitions and examples.