[Campbell Biology P.423] Which of the following are mechanisms by which specific transcripti... | Practice Question

Which of the following are mechanisms by which specific transcription factors, functioning as repressors, can inhibit gene expression in eukaryotes? Select all that apply

  • A: Binding directly to control element DNA, thereby blocking activator binding.
  • B: Interfering with the activator protein itself, preventing it from binding DNA.
  • C: Recruiting proteins that acetylate histones near gene promoters.
  • D: Recruiting proteins that remove acetyl groups from histones.
  • E: Directly binding to RNA polymerase II, preventing its initiation.

Explanation

The text describes several mechanisms: repressors can bind directly to control element DNA blocking activator binding , interfere with the activator protein itself, or indirectly affect chromatin structure by recruiting proteins that remove acetyl groups from histones leading to silencing .