[Campbell Biology P.438] According to Figure 18.23, which of the following genetic changes i... | Practice Question

According to Figure 18.23, which of the following genetic changes in a proto-oncogene specifically results in a hyperactive or degradation-resistant protein, rather than just an excess of normal protein?

  • A: Epigenetic changes causing inappropriate expression.
  • B: Translocation or transposition moving the gene under new controls.
  • C: Gene amplification, creating multiple copies of the gene.
  • D: Point mutation within the gene itself.

Explanation

Figure 18.23d explicitly shows that a 'Point mutation within the gene' results in a 'Hyperactive or degradation-resistant protein.' Other mechanisms a, b, c lead to an 'excess' of normal growth-stimulating protein, not altered protein function.