[Campbell Biology P.1020] Which of the following statements about autoimmune diseases are cor... | Practice Question

Which of the following statements about autoimmune diseases are correct according to the provided text? Select all that apply

  • A: They are characterized by the immune system becoming active against the body's own molecules, a loss of self-tolerance.
  • B: Systemic lupus erythematosus (lupus) primarily involves the immune system generating antibodies against the myelin sheaths of neurons.
  • C: Women are nine times more likely than men to have lupus and two to three times as likely to develop rheumatoid arthritis.
  • D: Regulatory T cells (Tregs) are an area of current research and help modulate immune system activity to prevent responses to self-antigens.
  • E: Type 1 diabetes is an autoimmune disease where the immune system targets the insulin-producing beta cells of the pancreas.

Explanation

Option A, C, D, and E are all directly stated in the text. Option B is incorrect because lupus involves antibodies against histones and DNA, while the myelin sheath target is characteristic of multiple sclerosis.