[Campbell Biology P.296] The "WHAT IF?" prompt in Figure 12.17 asks about the result if a ce... | Practice Question

The "WHAT IF?" prompt in Figure 12.17 asks about the result if a cell ignored either checkpoint and progressed through the cell cycle. Specifically, if a cell ignored the M checkpoint's stop signal despite chromosomes not being fully attached to spindle fibers, what would be the most likely consequence for the daughter cells?

  • A: The daughter cells would likely receive an abnormal number of chromosomes (aneuploidy).
  • B: The cell would undergo apoptosis immediately after ignoring the signal.
  • C: The cell would successfully complete division, but future divisions would be inhibited.
  • D: The cell would permanently enter the G0 state without dividing.

Explanation

The text states that the M checkpoint "ensures anaphase is completed and the chromosomes are well separated before cytokinesis can begin, thus avoiding chromosomal damage" and that "this mechanism ensures that daughter cells do not end up with missing or extra chromosomes." Therefore, if this checkpoint is ignored when chromosomes are not properly attached, daughter cells will receive an incorrect number of chromosomes aneuploidy .