[Campbell Biology P.295] According to the text, what is the direct consequence if some kinet... | Practice Question

According to the text, what is the direct consequence if some kinetochores remain unattached to spindle microtubules at the M checkpoint?

  • A: The cell immediately exits the cell cycle and enters the G₀ phase.
  • B: Anaphase is delayed until all chromosomes are properly attached to the spindle.
  • C: MPF activity significantly decreases, leading to premature cytokinesis.
  • D: Cyclin synthesis is inhibited, preventing the formation of new MPF molecules.

Explanation

The text explicitly states regarding the M checkpoint: 'Anaphase, the separation of sister chromatids, does not begin until all the chromosomes are properly attached to the spindle at the metaphase plate.' This mechanism ensures that each daughter cell receives a complete set of chromosomes.