[Campbell Biology P.218] Which of the following statements accurately compares oxidative pho... | Practice Question

Which of the following statements accurately compares oxidative phosphorylation and substrate-level phosphorylation, based on the provided text?

• A: Oxidative phosphorylation relies on an electron transport chain and chemiosmosis for ATP synthesis, accounting for almost 90% of ATP, while substrate-level phosphorylation involves direct transfer of a phosphate group from an organic substrate to ADP.
• B: Both oxidative phosphorylation and substrate-level phosphorylation primarily occur in the cytosol and produce large amounts of ATP.
• C: Substrate-level phosphorylation requires an electron transport chain, whereas oxidative phosphorylation involves direct enzyme-mediated ATP synthesis.
• D: Oxidative phosphorylation is the primary method of ATP synthesis in glycolysis, while substrate-level phosphorylation is prominent in the citric acid cycle only.