[Campbell Biology P.1105] The text mentions that researchers are attempting to generate an ar... | Practice Question

The text mentions that researchers are attempting to generate an artificial Extracellular Matrix ECM for the repair or replacement of damaged tissues. Based on the description of ECM's role, what is the primary function this artificial ECM would aim to mimic to aid in guiding cell movements?

  • A: Forming wedge-shaped cells for invagination.
  • B: Providing a meshwork of secreted glycoproteins and other macromolecules that guides cell migration pathways.
  • C: Contracting to cause cells to elongate and converge.
  • D: Inducing programmed cell death in damaged cells.

Explanation

The section 'Cell Migration in Morphogenesis' states that 'Cell migration also involves the extracellular matrix ECM , the meshwork of secreted glycoproteins and other macromolecules lying outside the plasma membranes of cells.' It further explains, 'The ECM helps to guide cells in many types of movements, such as migration of individual cells and shape changes of cell sheets. Cells that line migration pathways regulate the movement of migrating cells by secreting specific molecules into the ECM.'