[Campbell Biology P.438] A patient is diagnosed with cancer, and genetic analysis reveals a ... | Practice Question

A patient is diagnosed with cancer, and genetic analysis reveals a mutation in their ras gene, resulting in a hyperactive Ras protein. Based on the provided text, what is the most likely consequence of this specific mutation on cell signaling?

  • A: The cell will produce an excess of cell cycle-inhibiting proteins.
  • B: The cells will undergo programmed cell death (apoptosis) at an increased rate.
  • C: The kinase cascade associated with cell growth will be continuously triggered, even in the absence of growth factors.
  • D: Chromatin will become more condensed, leading to repression of gene expression for cell cycle proteins.

Explanation

The text states that 'certain mutations in the ras gene can lead to production of a hyperactive Ras protein that triggers the kinase cascade even in the absence of growth factor, resulting in increased cell division.' This directly leads to uncontrolled cell proliferation.