[Campbell Biology P.480] Which of the following statements about Induced Pluripotent Stem iP... | Practice Question
Which of the following statements about Induced Pluripotent Stem iPS cells is incorrect ?
A: iPS cells are generated by reprogramming fully differentiated cells back to an ES-like state.
B: The reprogramming process typically involves introducing extra copies of specific 'stem cell' master regulatory genes into differentiated cells using a modified retrovirus.
C: iPS cells were first successfully generated and reported in 2013, providing an alternative to ES cells derived from donated embryos.
D: These 'deprogrammed' cells are considered pluripotent, similar to ES cells, and can potentially avoid immune rejection if derived from the patient's own cells.
Explanation
The text states that 'researchers succeeded in 2007 in learning how to turn back the clock in fully differentiated cells... The 'deprogrammed' cells are known as induced pluripotent stem iPS cells'. The year 2013 is mentioned as the first report of 'cloned human blastocysts' as a source of ES cells, which is a different method.