[Campbell Biology P.222] In eukaryotic cells, where are most enzymes of the citric acid cycl... | Practice Question

In eukaryotic cells, where are most enzymes of the citric acid cycle located, and which specific enzyme is an exception, residing in a different cellular compartment?

  • A: All enzymes are located in the inner mitochondrial membrane; none are exceptions.
  • B: Most enzymes are in the mitochondrial matrix, with the enzyme for step 6 (succinate dehydrogenase) being an exception in the inner mitochondrial membrane.
  • C: Most enzymes are in the cytoplasm, with the enzyme for step 3 (isocitrate dehydrogenase) being an exception in the mitochondrial matrix.
  • D: All enzymes are located in the mitochondrial matrix; none are exceptions.

Explanation

The text explicitly states: 'In eukaryotic cells, all the citric acid cycle enzymes are located in the mitochondrial matrix except for the enzyme that catalyzes step 6, which resides in the inner mitochondrial membrane.'