[Campbell Biology P.506] According to Figure 21.16 and the accompanying text, which of the f... | Practice Question
According to Figure 21.16 and the accompanying text, which of the following statements accurately describes the evolution of the TPA gene through exon shuffling?
A: The TPA gene acquired exons from epidermal growth factor, fibronectin, and plasminogen genes through exon shuffling, followed by duplication of the "kringle" exon.
B: Exon shuffling primarily involves random insertions of new DNA sequences into existing genes, leading to novel functions.
C: The "kringle" exon in the TPA gene originated solely from the epidermal growth factor gene, and its duplication occurred before exon shuffling.
D: Exon shuffling is a process that only occurs within a single gene, leading to rearrangements of its existing exons.
Explanation
The text and Figure 21.16 illustrate that TPA's gene evolution involved acquiring EGF, F fibronectin , and K plasminogen kringle exons via shuffling from ancestral genes, and the K exon then duplicated within the TPA gene.