[Campbell Biology P.300] The eukaryotic cell cycle is tightly regulated by a molecular contr... | Practice Question

The eukaryotic cell cycle is tightly regulated by a molecular control system involving cyclins, cyclin-dependent kinases Cdks , and checkpoints. Which of the following statements correctly describes a characteristic or function of this regulatory system?

  • A: Cyclins are enzymes that directly phosphorylate target proteins, driving the cell cycle forward.
  • B: The G1 checkpoint is often considered a critical 'restriction point' where a cell commits to dividing or exits the cell cycle to a non-dividing state.
  • C: Cancer cells primarily differ from normal cells by forming cell plates instead of undergoing cleavage, which allows them to divide unchecked.
  • D: Go-ahead signals for cell cycle checkpoints are solely generated by internal signals, such as DNA damage or incomplete chromosome alignment.
  • E: Malignant tumors are characterized by their inability to undergo metastasis due to strict anchorage dependence.

Explanation

The text explicitly states that 'important checkpoints occur in G1, G2, and M phases.' For the G1 checkpoint, it is widely recognized in biology as the 'restriction point' where the cell makes a key decision to either commit to division or enter a non-dividing G0 state. This aligns with the 'TEST YOUR UNDERSTANDING' section's summary of checkpoints.