[Campbell Biology P.441] According to the text, which three signal receptors are identified ... | Practice Question

According to the text, which three signal receptors are identified as primarily involved in regulating cell growth and division in breast cancer, and what type of receptor is HER2?

  • A: Estrogen receptor alpha (ERα), Progesterone receptor (PR), HER2; HER2 is a G protein-coupled receptor.
  • B: Estrogen receptor alpha (ERα), Progesterone receptor (PR), HER2; HER2 is a receptor tyrosine kinase (RTK).
  • C: Estrogen receptor alpha (ERα), HER2, HER3; HER2 is a steroid receptor.
  • D: Progesterone receptor (PR), HER2, HER3; HER2 is a receptor tyrosine kinase (RTK).

Explanation

The text explicitly states: "They identified four major subtypes of breast cancer that differ in their expression of three signal receptors involved in regulating cell growth and division: Estrogen receptor alpha ERα , Progesterone receptor PR , HER2, a type of receptor called a receptor tyrosine kinase RTK ; other RTKs are also present, such as HER3". Therefore, ERα, PR, and HER2 are the three primary signal receptors, and HER2 is an RTK.